S-Adenosyl methionine (SAM-e)

Max points: 5 Type: Podcast

This episode explores SAMe (S-adenosylmethionine), a natural compound with promising benefits for mood disorders. The hosts explain how it works in neurotransmitter production, review clinical studies comparing SAMe with antidepressants, discuss dosage, side effects, costs, and highlight when it may be a safe, effective treatment option.

Channel: Beautiful Minds Wellness Duration: 0:39:26

Questions

1. Which biochemical process is emphasized as central to SAMe's mental health effects?

Beta-oxidation Glycolysis Phosphorylation Transmethylation

2. What key safety caution did the hosts highlight for certain patients considering SAMe?

Commonly documented serotonin syndrome with all SSRIs Frequent permanent hair loss Universal risk of kidney failure Potential for mania/hypomania in bipolar disorder

3. What does SAMe stand for, as discussed in the episode?

Sarcosine-methyl-ester Serine–aspartate methyl ether S-adenosyl-melatonin S-adenosylmethionine

4. What total daily dosing range do the hosts commonly suggest many adults may land on with SAMe (divided doses)?

800–1600 mg/day 5000–10000 IU/day 50–100 mg/day 5–10 mg/day

5. Which neurotransmitter synthesis is mentioned as influenced by SAMe's methyl-donor action?

Histamine only Serotonin Endorphins GABA only

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